Methyl 3-{[(2,6-difluorophenyl)sulfonyl]aMino}-2-fluorobenzoate
Methyl 3-{[(2,6-difluoropheyl)sulfonyl]amino}-2-fluorabenzoate
CAS: 1195768-19-4
Molecular Formula: C14H10F3NO4S
Methyl 3-{[(2,6-difluorophenyl)sulfonyl]aMino}-2-fluorobenzoate - Names and Identifiers
Methyl 3-{[(2,6-difluorophenyl)sulfonyl]aMino}-2-fluorobenzoate - Physico-chemical Properties
| Molecular Formula | C14H10F3NO4S |
| Molar Mass | 345.29 |
| Density | 1.507±0.06 g/cm3(Predicted) |
| Boling Point | 445.4±55.0 °C(Predicted) |
| pKa | 6.68±0.10(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
Methyl 3-{[(2,6-difluorophenyl)sulfonyl]aMino}-2-fluorobenzoate - Introduction
Methyl 3-{[(2,6-difluoropheyl)sulfonyl]amino}-2-fluorabenzoate, also known as fluorobenzoic acid 2,6-difluorophenylsulfonamide Methyl ester, is an organic compound. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: colorless or light yellow liquid
-molecular formula: C13H9F3NO4S
-Molecular weight: 347.27g/mol
-Melting point: 52-54 ° C
-Boiling point: 315 ° C
-Density: 1.559g/cm3
Use:
Methyl 3-{[(2,6-difluoropheyl)sulfonyl]amino}-2-fluorabenzoate is commonly used as an important intermediate in organic synthesis, and is used to prepare compounds such as drugs, dyes and pesticides. It can be used as a sulfonamido protecting reagent, participate in the preparation of acid chlorides, and can be used for the protection of aromatic amines.
Preparation Method: The preparation method of
Methyl 3-{[(2,6-difluoropheyl)sulfonyl]amino}-2-fluorabenzoate is mainly carried out by the following steps:
1.2,6-difluorobenzoic acid reacts with thionyl chloride to generate 2,6-difluorophenyl sulfonyl chloride.
2.2,6-difluorophenyl sulfonyl chloride reacts with methanol to generate 2,6-difluorophenyl sulfonate methyl ester.
3. The Methyl 2,6-difluorophenyl sulfonate is reacted with Methyl aminofluorobenzoate to produce the final product Methyl 3-{[(2,6-difluoropheyl)sulfonyl]amino}-2-fluorabenzoate.
Safety Information:
The specific hazards and safety measures of Methyl 3-{[(2,6-difluoropheyl)sulfonyl]amino}-2-fluorabenzoate should be evaluated according to the specific application scenarios and conditions of the compound. Therefore, when using or handling this compound, please refer to the product's Safety Data Sheet (MSDS) and follow the appropriate safety practices. This can avoid potential hazards and injuries and ensure personal safety. If you come into contact with this compound, rinse immediately with plenty of water and seek medical assistance.
Nature:
-Appearance: colorless or light yellow liquid
-molecular formula: C13H9F3NO4S
-Molecular weight: 347.27g/mol
-Melting point: 52-54 ° C
-Boiling point: 315 ° C
-Density: 1.559g/cm3
Use:
Methyl 3-{[(2,6-difluoropheyl)sulfonyl]amino}-2-fluorabenzoate is commonly used as an important intermediate in organic synthesis, and is used to prepare compounds such as drugs, dyes and pesticides. It can be used as a sulfonamido protecting reagent, participate in the preparation of acid chlorides, and can be used for the protection of aromatic amines.
Preparation Method: The preparation method of
Methyl 3-{[(2,6-difluoropheyl)sulfonyl]amino}-2-fluorabenzoate is mainly carried out by the following steps:
1.2,6-difluorobenzoic acid reacts with thionyl chloride to generate 2,6-difluorophenyl sulfonyl chloride.
2.2,6-difluorophenyl sulfonyl chloride reacts with methanol to generate 2,6-difluorophenyl sulfonate methyl ester.
3. The Methyl 2,6-difluorophenyl sulfonate is reacted with Methyl aminofluorobenzoate to produce the final product Methyl 3-{[(2,6-difluoropheyl)sulfonyl]amino}-2-fluorabenzoate.
Safety Information:
The specific hazards and safety measures of Methyl 3-{[(2,6-difluoropheyl)sulfonyl]amino}-2-fluorabenzoate should be evaluated according to the specific application scenarios and conditions of the compound. Therefore, when using or handling this compound, please refer to the product's Safety Data Sheet (MSDS) and follow the appropriate safety practices. This can avoid potential hazards and injuries and ensure personal safety. If you come into contact with this compound, rinse immediately with plenty of water and seek medical assistance.
Last Update：2024-04-09 20:48:19
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Product Name: Methyl 3-(2,6-difluorophenylsulfonamido)-2-fluorobenzoate Visit Supplier Webpage Request for quotationCAS: 1195768-19-4
Tel: +86-400-900-4166
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Product Name: Methyl 3-(2,6-difluorophenylsulfonamido)-2-fluorobenzoate Visit Supplier Webpage Request for quotationCAS: 1195768-19-4
Tel: +86-18821248368
Email: Int06@meryer.com
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Product Name: Methyl 3-{[(2,6-difluoropheyl)sulfonyl]aMino}-2-fluorabenzoate Visit Supplier Webpage Request for quotation
CAS: 1195768-19-4
Tel: 18301782025
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CAS: 1195768-19-4
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View History
Methyl 3-{[(2,6-difluorophenyl)sulfonyl]aMino}-2-fluorobenzoate
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他利那新 D-酒石酸盐
双椰油烷基甲基叔胺
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二溴4-硝基苯酚
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Baloxavir D4Q: What is Baloxavir D4 Q: What is the CAS Number of Baloxavir D4
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